Table 1.
List of behaviors tested on the CRS-R protocol and associated scores.
Threshold behaviors and associated diagnosis are shown in bold.
Fig 1.
Sample calculation of the average probabilistic minimal clinically important difference (pMCID) for a 1-point change in CRS-R total score across all diagnoses. In brief, the pMCID for a 1-point change is calculated by taking the ratio of the number of 1-point changes that result in a new threshold behavior (numerator) over the number of all possible 1-point changes (denominator). (Note: While not depicted, the calculation also includes “net” 1-point changes; e.g., where a 1-point decrease is observed in one subscale and a 2-point increase is observed on a different subscale; see methods for full detail).
Table 2.
Probability of patient attaining a new threshold behavior given an observed 1-, 2-, and 3-point change in CRS-R (including all combinations).
Table 3.
Probability of patient attaining a new threshold behavior given an observed 1-, 2-, and 3-point change in CRS-R (excluding impossible combinations).
Table 4.
Probability of patient attaining a new threshold behavior given an observed 1-, 2-, and 3-point change in CRS-R (excluding impossible combinations) if Consistent Movement to Command is reassessed to index eMCS.