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Table 1.

PICOT Table summarizing research question and parameters of interest.

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Table 2.

Study characteristics.

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Fig 1.

PRISMA flowchart of studies included in the systematic review.

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Fig 2.

Risk of bias graph of randomized studies.

Review authors’ judgements about each risk of bias item presented as percentages across all included studies. Blank spaces are present where a study did not evaluate a specific outcome(s).

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Fig 3.

Risk of bias summary of randomized studies.

Review authors’ judgements about each risk of bias item for each included study. Blank spaces are present where a study did not evaluate a specific outcome(s).

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Fig 4.

Risk of bias graph, Parienti et al., 2014.

Review authors’ judgements about each risk of bias item presented as percentages across all included studies. Blank spaces represent domain categories where there was no information available to adequately assess the domain.

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Fig 5.

Risk of bias summary, Parienti et al.

2014. Review authors’ judgements about each risk of bias item for each included study. Blank spaces are present where a study did not evaluate a specific outcome(s).

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Table 3.

Summary of data for CRBSI outcome.

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Table 4.

Summary of data for CVAD colonization outcome.

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Table 5.

Summary of data for CVAD occlusion outcome.

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