Table 1.
Characteristics of healthy participants.
Fig 1.
Capillaries are depicted more clearly with extension (IST7.6, IST12.0, and IST20) of the interscan time; OCTA images of the healthy macular area in the healthy eye.
A, The averaged OCTA image of a 4 × 4 mm2 macular area created by averaging ten OCTA images obtained at IST7.6. B, The averaged OCTA image of a 0.8 × 0.8 mm2 area around the FAZ magnified from image A. C, Binarized image of the capillaries from image B created using the software made by Canon Inc. D, The area of FAZ obtained from image C. E, The OCT B-scan image and decorrelation signal of B. No decorrelation signal is observed (white arrow). F, The averaged OCTA image of a 4 × 4 mm2 macular area created by averaging ten OCTA images obtained at IST12.0. G, The averaged OCTA image of a 0.8 × 0.8 mm2 area around the FAZ magnified from image E. H, Binarized image of the capillaries from image F created using the software made by Canon Inc. An additional capillary is depicted in image G, compared with the OCTA image obtained at IST7.6 (White arrow). I, The area of FAZ obtained from image G. J: The OCT B-scan image and decorrelation signal of G. A decorrelation signal not depicted in E is observed (white arrow). K The OCT B-scan image and G decorrelation signal: No decorrelation signal is confirmed (white arrow). The averaged OCTA image of a 4 × 4 mm2 macular area was created by averaging ten OCTA images obtained at IST20.6. M, The averaged OCTA image of a 0.8 × 0.8 mm2 area around FAZ magnified from image I. N, A binarized image of the capillaries from image J is created using software made by Canon Inc. An additional capillary is depicted in image G compared with the OCTA images obtained at IST7.6 and IST12.0 (White arrow). O, The area of FAZ obtained from image K. P, The OCT B-scan image and decorrelation signal of M. A decorrelation signal not depicted in E is observed (white arrow).
Fig 2.
Capillaries become more intense with each extended interscan time (IST7.6, IST12.0, and IST20.6); OCTA images of the healthy macular area in the healthy eye.
A, The averaged OCTA image of a 4 × 4 mm2 macular area created by averaging ten OCTA images obtained at IST7.6. B, The averaged OCTA image of a 0.8 × 0.8 mm2 area around the FAZ magnified from image A. C, Binarized image of the capillaries from image B created using the software made by Canon Inc. D, The area of FAZ obtained from image C. E, The OCT B-scan image and decorrelation signal of B. No decorrelation signal is observed (white arrow). F, The averaged OCTA image of a 4 × 4 mm2 macular area created by averaging ten OCTA images obtained at IST12.0. G, The averaged OCTA image of a 0.8 × 0.8 mm2 area around the FAZ magnified from image E. The capillary is more intense at IST12.0 than that at IST7.6 (White arrow). H, Binarized image of the capillaries from image F created using the software made by Canon, Inc. I, The area of FAZ obtained from image G. J: The OCT B-scan image and decorrelation signal of G. A decorrelation signal not depicted in E is observed (white arrow). The averaged OCTA image of a 4 × 4 mm2 macular area is created by averaging ten OCTA images obtained at IST20.6. L, The averaged OCTA image of a 0.8 × 0.8 mm2 area around FAZ magnified from image I. The capillaries are more intense at IST20.6 than that at IST12.0 (White arrows). M, A binarized image of capillaries from image J is created using software made by Canon Inc. N, The area of FAZ obtained from image K. O The OCT B-scan image and L decorrelation signal The decorrelation signal increased compared to that in E and J (white arrow).
Fig 3.
Comparison of the FAZ areas obtained at IST7.6 and IST12.0.
In the graph on the left, the vertical axis represents the FAZ area corrected by the axial length obtained at IST7.6 and IST12.0, whereas the horizontal axis represents IST. In the graph on the right, the vertical axis represents the area of FAZ obtained at IST7.6 and IST12.0 divided by the area of FAZ obtained at IST7.6; the horizontal axis represents IST. The FAZ areas decreased significantly at IST12.0 compared with that at IST7.6.
Fig 4.
Comparison of FAZ areas obtained at IST7.6 and IST20.6.
In the graph on the left, the vertical axis represents the FAZ area corrected by the axial length obtained at IST7.6 and IST20.6, whereas the horizontal axis represents IST. In the graph on the right, the vertical axis represents the area of FAZ obtained at IST7.6 and IST20.6 divided by the area of FAZ obtained at IST7.6; the horizontal axis represents IST. The FAZ areas decreased significantly at IST20.6 compared with that at IST7.6.