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Table 1.

Description of screening tools deployed.

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Table 2.

Results of simplified visual inspection checklist.

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Table 3.

Parameters of DD-SIMCA models and performances in terms of sensitivity and specificity.

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Fig 1.

Ciprofloxacin DD-SIMCA acceptance plots (a priori model).

A: DD-SIMCA model with calibration and validation sets; B: DD-SIMCA model with test sets. For A and B, samples are considered as belonging to the target class if they are below the threshold in the left corner of the plot. This model is the initial a priori one before applying bootstrapping analysis.

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Fig 1 Expand

Fig 2.

Metronidazole DD-SIMCA acceptance plots (a priori model).

A: DD-SIMCA model with calibration and validation sets; B: DD-SIMCA model with test sets. For A and B, samples are considered as belonging to the target class if they are below the threshold in the left corner of the plot. This model is the initial a priori one before applying bootstrap analysis.

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Fig 2 Expand

Fig 3.

Ciprofloxacin DD-SIMCA new acceptance plots with optimization of the calibration set (a posteriori model).

A: DD-SIMCA model with calibration and validation sets; B: DD-SIMCA model with test set. For A and B, samples are considered as belonging to the target class if they are below the threshold in the left corner of the plot. This model is the initial a posteriori one before applying bootstrap.

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Fig 3 Expand

Fig 4.

Metronidazole DD-SIMCA new acceptance plots with optimization of calibration set (a posteriori model).

A: DD-SIMCA model with calibration and validation sets; B: DD-SIMCA model with test sets. For A and B, samples are considered as belonging to the target class if they are below the threshold in the left corner of the plot. This model is the initial a posteriori one before applying bootstrap.

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Fig 4 Expand

Fig 5.

Cards of samples tested for specificity determination.

A) testing of a metronidazole sample; B) testing of moxifloxacin sample; C) testing of levofloxacin sample; D) testing of norfloxacin sample; E) testing of ofloxacin sample. Lanes D and L were positive with blue and orange colors respectively for cards C (Levofloxacin sample), D (Norfloxacin samples), and E (Ofloxacin samples). The coloration of lane D for card B (Moxifloxacin) tends to green color.

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Fig 5 Expand