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Table 1.

Inclusion and exclusion criteria for cases and controls.

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Fig 1.

Example of volumetric analysis.

The volumetric analysis of a right temporal HGG is shown in a 3-dimensional reconstruction, as well as in axial, sagittal and coronal planes. The tumor volume as determined based on contrast-enhanced T1-weighted images is highlighted in red.

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Table 2.

Patient characteristics.

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Table 2 Expand

Fig 2.

Tumor volumes of HGG patients during and before the COVID-19 pandemic.

Boxplot diagrams of preoperative tumor volumes are shown for patients treated during the first year of the COVID-19 pandemic (red) or before COVID-19 (blue). While median volumes were slightly higher in patients treated during the first year of the COVID-19 pandemic, no statistically significant difference was detected between the two study groups.

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Fig 3.

Interval to surgery in HGG patients during and before the COVID-19 pandemic.

Boxplot diagrams of the interval to surgery are shown for patients treated during the first year of the COVID-19 pandemic (red) or before COVID-19 (blue). Median interval to surgery was significantly shorter in patients treated during the first year of the COVID-19 pandemic.

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Fig 4.

Overall patient survival in HGG patients during and before the COVID-19 pandemic.

Kaplan-Meier curves of overall patient survival are shown for patients treated during the first year of the COVID-19 pandemic (red) or before COVID-19 (blue). There was no significant survival difference between patients treated during the first year of the COVID-19 pandemic and patients treated before COVID-19.

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Fig 4 Expand