Table 1.
The basic characteristic of the studied population.
Fig 1.
Serum levels of hsCRP, ICAM-1, and VCAM-1.
a) Serum levels of hsCRP were elevated in OSA patients compared to controls, and the severe-OSA group represents a higher concentration of hsCRP compared with mild-OSA and moderate-OSA groups. b) Serum concentration of ICAM-1 was higher in the OSA group compared to controls, and the severe-OSA group indicated higher ICAM-1 compared to the mild-OSA group. c) Patients with OSA were found to have a higher concentration of VCAM-1 compared to controls. ns, not significant; * p<0.05, ** p<0.01, *** p<0.001 and **** p<0.0001.
Fig 2.
a) miR125a levels increased in patients with OSA compared to controls, and in the severe-OSA group compared to the mild-OSA group. b) miR126 concentration was lower in OSA compared to controls and in the severe-OSA group compared to the mild-OSA group. c) circulating mi146a were found to be higher in OSA patients in comparison to controls, and mild-OSA had a lower concentration of miR146a-5p compared with moderate-OSA and severe-OSA groups. ns, not significant; * p<0.05, ** p<0.01, *** p<0.001 and **** p<0.0001.
Table 2.
Pearson correlation of miR125a, miR126, and miR146a-5p with other variables.
Table 3.
Odds ratio (OR) of the OSA presence according to circulating levels of miRs.
Fig 3.
ROC curve for the diagnostic ability of a) miR125a, b) miR126, and c) miR146a-5p.