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Fig 1.

Study flow diagram.

COVID-19, coronavirus disease 2019; ARDS, acute respiratory distress syndrome; HFNC, high-flow nasal cannula.

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Fig 1 Expand

Table 1.

Baseline characteristics of patients with COVID-19 associated ARDS who commenced HFNC therapy.

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Table 1 Expand

Fig 2.

Daily ROX index values between patients in the HFNC failure group and those in the HFNC success group.

HFNC, high-flow nasal cannula; ROX, respiratory rate-oxygenation.

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Fig 2 Expand

Fig 3.

The discriminative ability of ROX index, SpO2/FiO2, FiO2, RR, and SpO2 in determining HFNC failure.

HFNC, high-flow nasal cannula; ROX, respiratory rate-oxygenation; RR, respiratory rate.

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Fig 3 Expand

Table 2.

Diagnostic performance of ROX index cut-offs in determining HFNC failure.

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Table 2 Expand

Table 3.

Diagnostic performance of the ROX index compared with that of other respiratory parameters in determining HFNC failure.

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Table 3 Expand