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Fig 1.

Plantar surface assessment locations.

Thirteen locations per foot were evaluated with both a hand applied monofilament and the automated tool.

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Fig 1 Expand

Fig 2.

Automated tool and homing sequence protocol.

a) Automated tool which applies a monofilament through the perforated foot plate until contact with the plantar surface, b) Homing sequence protocol used to determine threshold sensitivity per location. Units are in gF.

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Fig 2 Expand

Fig 3.

Probe subassembly.

Monofilament (Magenta), Load Cell (Green), Stepper Motor (Yellow).

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Fig 3 Expand

Fig 4.

Foot clamping mechanism.

Perforated Foot Plate (Dark Blue), Aluminum 80/20 Extrusions (White), Toe Clamp (Maroon), Foot Clamp Base (Magenta), Foot Clamp (Green), and Ankle Holder (Blue).

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Fig 4 Expand

Fig 5.

Automated tool chassis.

Aluminum 80/20 Extrusions (White), Camera Mounting Plate Green), Camera Mount (Yellow), and Logitech Brio Webcam (Blue).

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Fig 5 Expand

Fig 6.

Foot plate.

Acrylic perforated foot plate with Logitech Brio webcam and Probe Subassembly visible.

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Fig 6 Expand

Fig 7.

Gantry subassembly.

Probe Subassembly (Magenta), Stepper Motor (Blue/Black), Belts (Black), Pulley (Orange), Linear Motion Rods (Yellow), Coupling (Bronze).

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Fig 7 Expand

Fig 8.

Threshold sensitivity maps.

a) Subject from Group 1, b) Subject from Group 2, c) Subject from Group 3.

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Fig 8 Expand

Fig 9.

Linear regression plots.

a) TSI Norm vs Age: Group 1 (R2 = 0.3422, P = 0.004); Group 2 (R2 = 0.0014, P = 0.86); Group 3 (R2 = 0.0083, P = 0.69), b) TSI Norm vs BMI: Group 1 (R2 = 0.0008, P = 0.90); Group 2 (R2 = 0.1144, P = 0.091); Group 3 (R2 = 0.0016, P = 0.58), c) TSI Norm vs ABI: Group 1 (R2 = 0.0305, P = 0.44); Group 2 (R2 = 0.1208, P = 0.082); Group 3 (R2 = 0.078, P = 0.21), d) TSI Norm vs FBS: Group 1 (R2 = 0.1819, P = 0.054); Group 2 (R2 = 0.0022, P = 0.82); Group 3 (R2 = 0.0692, P = 0.24), e) TSI Norm vs HbA1c: Group 1 (R2 = 0.4124, P = 0.12); Group 2 (R2 = 0.004, P = 0.76); Group 3 (R2 = 0.0628, P = 0.26).

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Fig 9 Expand

Table 1.

Statistical analysis summary.

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Table 1 Expand