Fig 1.
Flow chart of study selection process.
Table 1.
Characteristics of included studies.
Table 2.
Assessment of methodological quality by NOS.
Fig 2.
Forest plots of showing the effects of PTU vs MMI on congenital anomalies.
Fig 3.
Forest plots of showing the effects of PTU vs shift between PTU and MMI on congenital anomalies.
Fig 4.
Forest plots of showing the effects of PTU vs MMI on hepatotoxicity.
Fig 5.
Forest plots of showing the effects of PTU vs MMI on miscarriage.
Fig 6.
Funnel plot of congenital anomalies of PTU vs MMI.