Table 1.
Study questions.
Table 2.
Inclusion and exclusion criteria.
Fig 1.
Schedule of enrolment, interventions, and follow-up of the FinnTrunk study.
The specific time points are listed in the columns and the events are given in the rows. Participants will be randomly allocated to EVLA without (x1) or with (x2) concomitant UGFS before procedure at the treatment visit. All participants will have a follow-up visit at 3 months, 1 year, 3 years, and 5 years. If found necessary, the varicose tributaries can be treated at any of the follow-up visits. Abbreviations: the Aberdeen Varicose Vein Questionnaire (AVVQ), (the clinical class of) the Clinical-Etiology-Anatomy-Pathophysiology classification (CEAP), endovenous laser ablation (EVLA), Duplex ultrasound (DUS), EuroQoL quality of life questionnaire (EQ-5D-5L), patient related outcome measures (PROMs), ultrasound-guided foam sclerotherapy (UGFS), the Venous Clinical Severity Score (VCSS), the Venous Disability Score (VDS). 1According to the randomized allocation (group 1) 2According to the randomized allocation (group 2) *If judged necessary by the patient (both groups).