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Fig 1.

A schematic diagram of collected data.

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Fig 1 Expand

Table 1.

Detailed demographic information of the collected datasets.

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Table 1 Expand

Fig 2.

Training strategy for developing sensitive classification networks using GAN inversion as a feature-extracting method.

The first step is an upstream task that trains the generative adversarial network (GAN). The second step classifies through linear probing and projection combination using GAN inversion.

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Fig 3.

False-negative case examples in the (A) internal test and (B) external validation datasets.

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Table 2.

Our final model’s scoliosis classification performance.

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Table 2 Expand

Fig 4.

Scoliosis classification performance within the number of projection head layers and downstream training samples.

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Fig 5.

Downstream validations relative to upstream pre-trained weight type.

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Table 3.

Performance metric comparison under a fixed 0.9 sensitivity and statistical analysis using independent t-test among different feature extractor weights.

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Table 3 Expand

Fig 6.

Example of a well-reconstructed normal sample.

(Left) original chest X-ray. (Right) Reconstructed image using the GAN inversion technique. The encoding generator was only trained with chest X-ray images with scoliosis.

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Table 4.

Image-reconstruction quality metrics of scoliosis and normal downstream training sets.

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Table 4 Expand

Fig 7.

Generated CXR samples.

(Left) Samples from a model trained on an imbalanced dataset (our method). (Right) Samples from a model trained on a balanced dataset. Red box: a sample radiograph that can be diagnosed as a normal spine in generated samples.

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Fig 8.

Two manipulated image examples.

Note that scoliosis forms traverse between levoscoliosis and dextroscoliosis.

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