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Fig 1.

Study population.

Flowchart (A) and HCP distribution according to specialty (ED: Emergency Department; ICU: Intensive Care Unit). Surgery encompasses visceral, thoracic, and vascular surgery, neurosurgery, Gynecology, ENT, and orthopedics. RR response rate of participants screened.

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Table 1.

Participant’s demographical characteristics.

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Fig 2.

Assessment of sepsis knowledge and management skills.

Pie chart representation of responses of participants/respondents according to a five-category Likert scale. Assessment of baseline sepsis knowledge and management skills by either the entire study group (A) or by each category of health care professionals (B). Number of participants/respondents: 619 nurses, 358 physicians, and 149 paramedics.

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Fig 3.

Sepsis awareness.

Assessment of sepsis characteristics or features (i.e. urgency of care, severity, need for prompt evaluation, and context of appearance) according to a 5-category Likert scale by study participants. Asterisks represent the expected answer.

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Table 2.

Specific sepsis training among study participants.

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Fig 4.

Sepsis definitions and sepsis scores.

Evaluation of the definition of sepsis (A) and of scores (SOFA, SIRS, qSOFA, MEWS and APACHE II) as a sepsis defining tool (B) or a bedside predictor of sepsis mortality (C). Underlined answers are correct. Abbreviations: MEWS (modified early warning score), APACHE II (acute physiology and chronic health evaluation II).

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Fig 5.

Clinical vignette.

Management of a patient with suspected sepsis and a qSOFA of 2 (i.e., respiratory rate of 25 per min and a Glasgow Coma Scale score of 13) by paramedics (A), nurses (B), or physicians (C). In panel C, assessment of evaluation tools (step 1) and of management (step 2). Abbreviations: GP (general practitioner), ED (emergency department), EEG (electroencephalogram), IVIG (intravenous immunoglobulins). Underlined answers are expected answers, dotted underlined answers should be considered.

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Fig 6.

Multivariable analysis.

Notes: Abbreviations: C/I correct/incorrect; OR: Odds ratio; IC 95%: Confidence interval. OR: gray vertical line is 1.0; the heavy black line represents the OR and the light blacklines represent the spread of the confidence interval.

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