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Fig 1.

Cancer histology in metastatic lymph nodes.

(A,B) Tubular. (C,D) Cribriform. (E,F) Poorly differentiated. (G,H) Mucinous. Original magnification: A, C, E, G: 100×; B, D, F, H: 400×. Staining: Hematoxylin and eosin.

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Fig 2.

Homogeneous cancer histology presenting in a single metastatic lymph node.

(A,B) Tubular adenocarcinoma. (C,D) Cribriform adenocarcinoma. (E,F) Poorly differentiated adenocarcinoma. (G,H) Mucinous adenocarcinoma. Original magnification: A, C, E, G: 40×; B, D, F, H: 100×. Staining: Hematoxylin and eosin.

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Fig 2 Expand

Table 1.

Histologic cancer types in the lymph nodes of 119 node-positive patients with colorectal cancer.

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Fig 3.

Kaplan–Meier plots of cancer-specific survival (CSS) in node-positive disease.

CSS when all metastatic lymph nodes (mLNs) showed tubular carcinoma (“tub”), all mLNs showed cribriform carcinoma (“cri”), and some mLNs showed either tubular or cribriform carcinoma (“tub+cri”). All analyzed patients had a primary tumor classified as moderately differentiated adenocarcinoma.

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Fig 3 Expand