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Fig 1.

Study selection flow diagram.

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Table 1.

Characteristics of included studies.

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Table 1 Expand

Fig 2.

QUADAS-2 results in each study.

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Fig 2 Expand

Fig 3.

Deek’s funnel plot.

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Fig 3 Expand

Table 2.

Summary of each included studies.

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Table 2 Expand

Fig 4.

The forest plot of the pooled sensitivity and specificity.

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Fig 4 Expand

Fig 5.

The SROC (a) the pooled SROC; (b) the SROC of types of AMD; (c) the SROC of types of images; (d) the SROC of variants of CNNs; (e) the SROC of Networks.

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Table 3.

Subgroup analyses and meta regression results.

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Table 3 Expand