Fig 1.
Flow chart detailing how study population was selected from all patients who underwent home oxygen evaluation during the study period.
Table 1.
Comparison of clinical and demographic characteristics between subjects with exertional hypoxemia with and without immediate improvements in 6MWD with supplemental oxygen.
Table 2.
Oxygenation and other 6-minute walk testing parameters between responders and non-responders.
Fig 2.
Survival curves between immediate responders and non-responders to oxygen therapy.
A. Kaplan Meier estimates of survival. Responders (green line) are subjects who immediately improved their 6-minute walk distance > 54 m when walking on oxygen compared to their baseline distance walked on room air. Non-responders improved < 54 m (blue line). The graphs illustrate time-to-event (death) with a median follow-up time of 3 years. B. Cox regression analysis of survival. The Cox regression model included age, comorbidities (Charlson Comorbidity Index) and FEV1 as covariates. At the time subjects had a lung transplant or developed severe resting hypoxemia after group allocation, they were censored from the analysis. Green line corresponds to responders and blue line to non-responders.