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Fig 1.

Economic returns from academic and corporate licenses to biotechnology companies.

(a.) Effective royalty rate on $500M in net sales; (b.) Total reported deal size; (c.) Total precommercial payments. Analysis excludes licenses to pharmaceutical companies.

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Fig 1 Expand

Table 1.

Economic returns for biotechnology licenses by licensor and licensee.

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Table 1 Expand

Fig 2.

Economic returns from academic-biotech, corporate-biotech, and corporate-pharma licenses by development phase of lead product.

Effective royalty rate on $500M in net sales for (a.) Academic-biotech licenses; (b.) Corporate-biotech licenses; and (c.) Corporate-pharma licenses. Deal size for (d.) Academic-biotech licenses; (e.) Corporate-biotech licenses; and (f.) Corporate-pharma licenses. Precommercial payments for (g.) Academic-biotech licenses; (h.) Corporate-biotech licenses; and (i.) Corporate-pharma licenses. Development phase is defined as the development phase of the most advanced product (discovery, lead molecule, preclinical, phase 1, phase 2, phase 3, or approved). Phase 3 trials are not included in data describing academic licenses due to insufficient data. Note differences in the scale for the deal size and precommercial payments of different license classes.

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Fig 2 Expand

Table 2.

Economic returns for biotechnology licenses by license class and development phase.

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Table 2 Expand

Table 3.

Economic returns for biotechnology licenses by licensee and development phase.

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Table 3 Expand

Table 4.

Median regression coefficients by licensor, most advanced development phase and deal terms.

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Table 4 Expand