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Table 1.

Criteria used for grading the certainty of evidence.

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Fig 1.

The PRISMA flow diagram of the study selection process.

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Table 2.

Participant and study characteristics, and physiological adaptations and main findings.

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Table 2 Expand

Table 3.

Methodological quality and risk of bias of the included studies (PEDro scale).

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Fig 2.

Forest plots depicting studies using LL-BFRT compared to studies using LL-RT in muscle strength.

Forest plot comparing low-load resistance training with blood flow restriction (LL-BFR) and low-load resistance training alone (LL-RT) on muscle strength of a) chest press (1RM) b) shoulder flexion (dynamometry in kgs). Abbreviations: CI, confidence interval; IV, inverse variance; Random, random effects model; SE, standard error.

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Table 4.

Summary of evidence for the effects of LL-BFRT compared with LL-, HL-RT, or no exercise in muscle strength.

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Table 4 Expand

Fig 3.

Forest plots depicting studies using LL-BFRT compared to studies using HL-RT in muscle strength.

Forest plots comparing low-load resistance training with blood flow restriction (LL-BFRT) and high load resistance training alone HL-RT in strength of: a) chest press (1RM), and b) sensitivity analysis by removing one study (Thiebaud et al., 2013) that included substantially older participants. Abbreviations: CI, confidence interval; IV, inverse variance; Random, random effects model; SD, standard deviation.

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Fig 3 Expand

Table 5.

Summary of evidence for the effects of LL-BFRT compared with LL-, HL-RT, or no exercise in muscle size.

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Table 5 Expand