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Fig 1.

Patient selection flowchart.

2L: second-line; CT: chemotherapy; dx: diagnosis; IO: immunotherapy; NSCLC: non-small cell lung cancer; VA: Veterans Affairs.

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Table 1.

Patient demographic and clinical characteristics by 2L treatment.

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Table 2.

Multivariable logistic regression to assess association between patient characteristics and receipt of 2L IO vs CT.

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Table 2 Expand

Fig 2.

Kaplan–Meier plot of OS for patients who received 2L IO vs CT, from initiation of 2L therapy.

2L: second-line; CI: confidence interval; CT: chemotherapy; Est: estimated; HR: hazard ratio; IO: immunotherapy; OS: overall survival; Tx: treatment.

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Fig 2 Expand

Table 3.

Inverse probability weighting Cox proportional hazard regression to evaluate the effect of treatment on OS.

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Table 3 Expand

Table 4.

Summary of HCRU in 2L patients.

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Table 4 Expand

Table 5.

AE occurrence by 2L treatment.

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Table 5 Expand