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Fig 1.

Primary, secondary, and exploratory outcomes of the study.

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Fig 2.

Eligibility criteria for participants.

Abbreviations: ADT, androgen deprivation therapy; DM, diabetes mellitus; HbA1c, glycated hemoglobin; MR spectroscopy, magnetic resonance spectroscopy. *Within 3 months from enrollment. ** Participants who have contraindications to MRS but are otherwise eligible will be enrolled.

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Fig 2 Expand

Table 1.

Schedule of enrollment and assessments.

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Table 1 Expand

Fig 3.

Anticipated patterns of changes in plasma glucose concentrations according to the primary site of insulin resistance.

* *Based on information from Reference #33.

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Fig 3 Expand