Table 1.
Basic characteristics of the two study cohorts.
Table 2.
Descriptive data of physical function, muscle strength and physical performance on the two cohorts.
Fig 1.
Correlation analysis was significant between HAQ-DI and (A) DAS28-CRP, (B) swollen joints. (C) Tender joints, (D) CRP, (E) VAS pain scale, and (F) patients global scores in the North American cohort. Abbreviations: HAQ-DI, Health Assessment Questionnaire-Disability Index; DAS28-CRP, Disease Activity Score in 28 Joints–C-reactive protein; VAS, visual analogue scale.
Fig 2.
Correlation analysis was significant between HAQ-DI and (A) DAS28-CRP, (B) swollen joints. (C) Tender joints, (D) VAS pain scale, and (E) patients global scores in the Brazilian cohort. Abbreviations: HAQ-DI, Health Assessment Questionnaire-Disability Index; DAS28-CRP, Disease Activity Score in 28 Joints–C-reactive protein; VAS, visual analogue scale.
Fig 3.
Correlation analysis was significant between HAQ-DI and (A) handgrip test, (B) chair stand test, and (C) SPPB in North American cohort. Abbreviations: SPPB, Short Physical Performance Battery; kg, kilogram; sec, seconds.
Fig 4.
Correlation analysis was significant between HAQ-DI and (A) handgrip test, (B) chair stand test, and (C) TUG in the Brazilian cohort. Abbreviations: TUG, Timed-up-and-go test; kg, kilogram; sec, seconds.
Fig 5.
A. Mean and SD of muscle strength by handgrip test stratified by disability status of HAQ-DI. B. Median and (IQR) of muscle strength by chair test stratified by disability status of HAQ-DI. C. Median and (IQR) of physical performance by Timed up and go (TUG) test stratified by disability status of HAQ-DI. D. Median and (IQR) of physical performance by The Short Physical Performance (SPPB) test stratified by disability status of HAQ-DI. Independent Samples Kruskal-Wallis test for all analysis.
Table 3.
Comparison of physical function, muscle strength and physical performance (disease remission versus high disease activity).
Table 4.
Changes over time in self-reported physical function and clinical characteristics, muscle strength, and physical performance over time in the North American and Brazilian cohorts.
Table 5.
Evaluation of continuous variables those were associated with the HAQ-DI in longitudinal analyses.
The beta-coefficient represents the relationship between the change in the variable and the change in HAQ-DI over the same follow-up time.