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Fig 1.

Schematic representation of the study design.

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Table 1.

Summary of baseline survey measures.

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Fig 2.

Mean and range for each symptom by participant ID.

Values represent rating (0–100) on visual analogue scale in the study app.

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Fig 3.

Standard deviation (circles) and root mean square of successive differences (diamonds) for each symptom by participant ID.

Values represent rating (0–100) on visual analogue scale in the study app.

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Table 2.

Summary of symptom self-report values per participant.

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Fig 4.

Within-person associations between symptom pairs.

Solid line indicates zero, dotted line indicates mean of correlations. Correlations only reported for individuals where both symptoms had a median value greater than zero. Labels in each sub-figure indicate number of individual correlations reported and mean correlation coefficient.

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Fig 5.

Heatmap of unadjusted correlations between symptoms at the individual participant level.

Figure shows only those participants who experienced all relevant symptoms at sufficient level to be included in the correlation analysis.

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Fig 6.

Summary network of symptoms.

Between-subject network shows partial correlations based on individual participant mean values, Within-subject contemporaneous network maps statistically significant partial correlations of data points at the same time point; Within-subject Temporal network shows statistically significant partial correlations at lag(1) and autocorrelations. FTG, fatigue; PAI, pain; LIH, light-headedness; COG, cognitive difficulty; ANX, anxiety. BRE, breathlessness.

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Fig 7.

Within-subject contemporaneous symptom networks.

Figures show statistically significant partial correlations of data points at the same time point. FTG, fatigue; PAI, pain; LIH, light-headedness; COG, cognitive difficulty; ANX, anxiety. BRE, breathlessness.

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Fig 8.

Within-subject temporal (lagged) symptom networks.

Figures show statistically significant partial correlations of data between consecutive time point. FTG, fatigue; PAI, pain; LIH, light-headedness; COG, cognitive difficulty; ANX, anxiety. BRE, breathlessness.

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Table 3.

Distribution of summary measures of physical activity data at individual participant level.

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Fig 9.

Distribution of within-person correlations between objective activity from accelerometer and subjective measures of fatigue and demand (physical alone or combined physical, cognitive, and emotional).

All activity measures refer to the 3-hour period before app data entry except where indicated.

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Fig 10.

Symptoms in relation to peak period of physical activity.

Bold lines indicated participants (n = 7) in whom the moving average z-score (for either fatigue or overall unwellness) was ≥1.3 between 12 and 60 hours post peak. Pale lines represent other participants. Smoothed regression line fitted to data from the 7 participants only.

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Fig 11.

Distribution of individual participant values by PCR testing status.

Unknown category represents participants who did not have a PCR test during their initial illness. VAS = Visual Analogue Scale.

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