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Fig 1.

Screening flow chart for the systematic review and metaanalysis.

It includes selecting and exclusion reasons which followed Preferred Reporting Items for Systematic Review and Metaanalysis (PRISMA) statement.

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Table 1.

Basic characteristics of the included studies.

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Fig 2.

Duration of hospital stay of East-Asian Covid-19 patients treated with ACEI/ARB vs. untreated subjects.

The duration of hospital stay data of MD and 95% CI from 9 studies were pooled in this meta-analysis and the result of metaanalysis was described as a forest plot. (a) The whole group analysis; (b)The subgroup analysis of age;(c) The subgroup analysis of gender.

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Fig 2 Expand

Table 2.

Clinical outcomes of East-Asian Covid-19 patients treated with ACEI/ARB vs. untreated subjects (all studies).

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Table 2 Expand

Fig 3.

Severity of East-Asian Covid-19 patients treated with ACEI/ARB vs. untreated subjects.

The severity data of OR and 95% CI from 17 studies were pooled in this meta-analysis and the result of meta-analysis was described as a forest plot. (a) The whole group analysis; (b) The subgroup analysis of age; (c) The subgroup analysis of gender.

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Fig 4.

Mortality of East-Asian Covid-19 patients treated with ACEI/ARB vs. untreated subjects.

All-cause mortality data of OR and 95% CI from 23 studies were pooled in this meta-analysis and the result of meta-analysis was described as a forest plot. (a) The whole group analysis; (b) The subgroup analysis of age; (c) The subgroup analysis of gender.

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Fig 5.

Mortality of East-Asian Covid-19 patients treated with ACEI/ARB vs. untreated subjects (HT subgroup).

All-cause mortality data of OR and 95% CI from 20 studies were pooled in this meta-analysis and the result of meta-analysis was described as a forest plot. (a) The whole group analysis; (b) The subgroup analysis of age; (c) The subgroup analysis of gender.

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Fig 5 Expand

Fig 6.

Severity of East-Asian Covid-19 patients treated with ACEI/ARB vs. untreated subjects (HT subgroup).

The severity data of OR and 95% CI from 15 studies were pooled in this meta-analysis and the result of meta-analysis was described as a forest plot. (a) The whole group analysis; (b) The subgroup analysis of age; (c) The subgroup analysis of gender.

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Fig 6 Expand

Table 3.

Clinical outcomes of East-Asian Covid-19 patients treated with ACEI/ARB vs. untreated subjects (HT subgroup).

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Table 3 Expand