Fig 1.
Participant flow diagram of enrollment, allocation, follow-up, and analysis.
Table 1.
Participant demographics.
Fig 2.
Home usage from two representative participants during the 8-week Pre-TMR (top) and 8-week Post-TMR-1 (bottom) home trials.
Each graph indicates the number of hours the device was turned on (bar, with scale on left-hand axis) and the number of calibrations (dot, with scale on right-hand axis) performed for each day of the home trial. Days of no use were logged as 0 hours on the plots.
Table 2.
Pre- vs post-TMR 8-week home trial usage data.
Fig 3.
Changes in post-home trial outcome measures for 7 subjects from the Pre-TMR 8-week trial to the Post-TMR 8-week trial (Post-TMR-1, orange) and from the Pre-TMR 8-week trial the final Post-TMR 3 month trial (Post-TMR-2, red).
The SHAP, Box & Blocks, and Jebsen-Taylor showed the largest improvements Post-TMR-2 compared to Pre-TMR.
Table 3.
Outcome measures following home trial.
Fig 4.
32-channel EMG data collection setup (top) and results (bottom) for 6 subjects. Offline classification error rates are plotted for the system with increasing number of grips configured (left) and thumb and finger movements (right). Colors represent data collected Pre-TMR (grey) and Post-TMR (orange) optimized for a system using only 4 channels and all 32 channels. Standard deviations for the 4 channels are shown with error bars and for the 32 channel data with shaded bands.
Fig 5.
Reinnervated forearm skin of the two subjects who underwent targeted sensory reinnervation.
For both individuals, sensations referred from their missing hand were felt in their residual forearm. Referred sensations were localized to either the palmar side (red), the dorsal side (blue), or both (purple).
Table 4.
Subject TMR and TSR results.