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Table 1.

Significant associations between child maltreatment and DNA methylation.

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Table 1 Expand

Table 2.

Significant associations between depressive symptoms and DNA methylation.

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Table 2 Expand

Fig 1.

Mediation analyses.

(A) Adjusted model for NR3C1_2_CpG_49to52. (B) Adjusted model for SLC6A3_1_CpG_16. (C) Adjusted model for the index of cumulative methylation.

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Table 3.

Significant interactions between child maltreatment and DNA methylation predicting depressive symptoms.

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Table 3 Expand

Fig 2.

A visual representation of the association between child maltreatment and depressive symptoms according to a cumulative index of methylation.

Fig 2 depicts the conditional association between maltreatment experiences and depressive symptoms according to increasing DNAm levels, depicted in three equal groups.

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Fig 2 Expand