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Fig 1.

Flowchart of sample selection for derivation and validation of a clinical rule for chikungunya diagnosis.

aRT-PCR: real-time polymerase chain reaction (ZDC Molecular Kit, Fiocruz).

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Table 1.

Sociodemographic characteristics of suspected arbovirus cases, Rio de Janeiro, Brazil 2016–2019 (n = 3,214).

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Fig 2.

Presence of clinical signs and symptoms according to diagnosis, Rio de Janeiro, Brazil, 2016–2019 (n = 3,214).

OFI: Other febrile illness.

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Fig 2 Expand

Fig 3.

Odds ratio (OR) of clinical predictors according to chikungunya diagnosis (CHIK) in derivation (sample 1) and validation samples (sample 2).

A. Sample 1 (1,608): OR (95% CI, p−value). B. Sample 2 (1,606): OR (95% CI, p−value).

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Fig 3 Expand

Table 2.

Odds ratio (OR), β coefficients, and scores of clinical predictors for chikungunya diagnosis in the final multiple binary regression model*, sample 1 (n = 1,608).

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Table 2 Expand

Table 3.

Accuracy parameters for chikungunya case definitions by national and international health agencies, validation sample 2 (n = 1,606).

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Table 3 Expand