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Fig 1.

PRISMA flow diagram.

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Fig 2.

A framework for NLP workflow in clinical setting according to CRISP-DM reference model [18].

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Table 1.

List of items extracted.

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Fig 3.

a. Number of articles published each year; search was conducted on 1st July 2021. b. Number of articles by country of author institution.

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Table 2.

Operational assessment of the included articles against the proposed framework.

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Table 3.

Dataset characteristics.

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Fig 4.

Patient type studied in each article (chord diagram from circlize [61]).

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Fig 5.

Definition of an ADE as an entity or as a relation in the text; solid coloured rectangles represent entities and dashed line boxes over linking arrows represent relationships between entities.

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Table 4.

Methods, performance and evaluation measures.

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Table 5.

Summary of single best reported result for overall performance and ADE entity or relation class performance by task.

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Table 6.

Common errors described in error analyses.

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