Table 1.
Functional classification and quantification of transcripts and proteins identified in C. felis salivary gland homogenates.
Table 2.
Relative abundance of protein families found within the ‘secreted’ functional class.
Fig 1.
Amino acid alignment of members of the FS-H protein family.
Sequences from C. felis salivary glands (Cf_contig_XXXX) detected by LC-MS analysis with previously deposited identified FS-H members from the rat flea X. cheopis (Xc_XXX and ABMXXXXX) and scorpion toxins from Centruroides noxius (sp|P15223), Tityus obscurus (sp| H1ZZI4), Mesobuthus martensii (sp|P15228), Leiurus hebraeus (sp|P0C5I9) and Rhopalurus junceus (sp|E7CLP2). The conserved cysteine residues are shaded in black.
Fig 2.
Amino acid alignment acid phosphatases.
Human prostatic acid phosphatase (NP_001090.2) and acid phosphatases from X. cheopis (ABM55413.1, ABM55400.1, ABM55403.1, ABM55410.1, ABM55411.1, ABM55409.1) previously identified by mass spectrometry analysis in the flea salivary glands and C. felis acid phosphatases. The motifs containing the histidine residues relevant for the hydrolysis of phosphate monoesters are boxed in red.
Fig 3.
Amino acid alignment of C. felis cholinesterases.
C. felis sequences found in the mass spectrometry analysis were aligned with sequences from Torpedo californica (1EA5), Mus musculus (1MAA), Cimex lectularius (GU597837) and the human (sp|P06276) cholinesterases. The catalytic triad residues Ser, Glu and His are red-boxed.