Table 1.
Demographic and clinical features of neonates in Han and Uighur group.
Fig 1.
Mutations of UGT1A1 found in our study cohort.
(A) c. 211 G >A heterozygote (Gly71Arg); (B) c. 211 G >A homozygote (Gly71Arg) (C) c.1091C>T heterozygote (Pro364Leu).
Fig 2.
A typical chromatograph of capillary electrophoresis of UGT1A1 (TA)n promoter polymorphism followed by direct sequencing.
a(1–2) (TA)6 /(TA)6 homozygote; b(1–2) (TA)6/(TA)7 heterozygote. c(1–2) (TA)7 /(TA)7 homozygote; d(1–2) (TA)5 /(TA)6 homozygote.
Table 2.
Genotypes frequency of c.-3275T>G in enhance, (TA)n repeat polymorphism and *6 (c.211G > A, p.Arg71Gly) variant of UGT1A1 gene in Han vs Uighur groups.
Table 3.
The associations between TCB level and UGT1A1 mutation adjusted by age, gender and race: Linear regression analysis.
Table 4.
TCB levels of study neonates in the subgroup divided by UGT1A1 genotype.
Table 5.
Associations of UGT1A1 variants and neonate hyperbilirubinemia under different inheritage model assumptions: Logistic regression analysis.