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Fig 1.

CONSORT flow chart of screening, participation and analysis.

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Fig 1 Expand

Fig 2.

Schematic overview of the study design.

WR: Well-rested. SDP: Sleep Deprived.

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Fig 2 Expand

Fig 3.

Schematic overview of the order of tests.

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Fig 4.

Visual impression of the car weaving within a lane.

The Standard Deviation of Lateral Position (SDLP) is calculated as the standard deviation of the sway around the average position within the lane.

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Fig 4 Expand

Fig 5.

Schematic overview of data removal during a lane switch.

All data between three seconds before until three seconds after a lane switch is removed prior to analysis.

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Table 1.

Inter-subject, intra-subject, common variance, and minimal detectable effect size (MDES), calculated at the well-rested visit.

CoV: Coefficient of Variation.

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Table 2.

Results of driving-related parameters for both the simulator and GRIDT.

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Table 2 Expand

Fig 6.

Combined Bland-Altman plot for simulator (bias: -2.01 and 95% limits of agreement: -11.10 and 7.09) and GRIDT (bias: -0.860 and 95% limits of agreement: -4.33 and 2.61).

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Fig 6 Expand

Table 3.

Mean values (SD) of NeuroCart parameters.

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Table 3 Expand

Table 4.

Pearson correlations for the variables in different conditions.

Only correlations with at least one significant correlation (p < .05) are included in this overview.

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Fig 7.

Scatter plot of the SDLP measured by the simulator and the GRIDT for the well-rested morning (WRM), well-rested afternoon (WRA) and the sleep deprived (SD) assessments.

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Fig 7 Expand

Table 5.

Pearson correlations for the delta between sleep deprivation and well-rested morning for any parameter and the SDLP of the simulator and GRIDT.

Only correlations with at least one significant value (i.e., p ≤ .05) are presented.

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Table 5 Expand