Table 1.
Characteristics of patients on admission and during ICU stay.
Fig 1.
Matrix correlation of the indices from routine coagulation and ROTEM on admission.
TP: Prothrombin Time; aPTT: Activated Partial Thromboplastin Time; Fg: Fibrinogen; E: EXTEM; I: INTEM; F: FIBTEM; H: HEPTEM; CT: Clotting time; CFT: Clot formation time; A5: Clot amplitude 5 minutes after CT; MCF: Maximum clot firmness.
Table 2.
ROTEM, blood count and standard hemostasis on admission.
Fig 2.
Results of ROTEM tests with the graphical shape performed on admission showing both hypercoagulability and hypofibrinolysis.
In this patient, hypercoagulability was characterized by an EXTEM CFT result below normal range values (< 46 s), and EXTEM A5 and EXTEM MCF results above normal range values (> 52 mm and > 72 mm, respectively); hypofibrinolysis was characterized by EXTEM Li 60 > 96.5%. CT: Clotting time; CFT: Clot formation time; A5 –A10 –A20: Clot amplitude 5–10–20 minutes after CT; MCF: Maximum clot firmness.
Fig 3.
Prediction of the occurrence of thrombo-embolic events during ICU stay by coagulation indices on day 1 and day 4.
AUC: Area Under the Curve; E: EXTEM; CFT: Clot formation time; A5: Clot amplitude 5 minutes after CT; MCF: Maximum clot firmness; Li60: Lysis index at 60 minutes.
Fig 4.
Prediction of intubation during ICU stay by coagulation indices on day 1 and day 4.
AUC: Area Under the Curve; E: EXTEM; CFT: Clot formation time; A5: Clot amplitude 5 minutes after clotting time; MCF: Maximum clot firmness; Li60: Lysis index at 60 minutes.
Fig 5.
Prediction of ICU death by coagulation indices on day 1 and day 4.
AUC: Area Under the Curve; E: EXTEM; CFT: Clot formation time; A5: Clot amplitude 5 minutes after clotting time; MCF: Maximum clot firmness; Li60: Lysis index at 60 minutes.
Fig 6.
Prediction of intubation and/or ICU death by coagulation indices on day 1 and day 4.
AUC: Area Under the Curve; E: EXTEM; CFT: Clot formation time; A5: Clot amplitude 5 minutes after clotting time; MCF: Maximum clot firmness; Li60: Lysis index at 60 minutes.