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Fig 1.

Flow diagram showing the process for participant screening, enrolment and analyses for the study.

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Table 1.

Environmental conditions (means±SD, n = 20).

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Table 1 Expand

Fig 2.

Description of the experimental set-up.

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Fig 2 Expand

Table 2.

Cognitive performance values (means±SD).

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Table 2 Expand

Fig 3.

Results for cTOI (a), cOxyHb (b), cDeOxyHb (c), cTotHb (d) at rest and during the cognitive performance test. Values demonstrate the median, iqr, min, max values. Dots indicate the individual values of each participant. ⫪ p = 0.001 main difference between environments, * p = 0.001 to NN.

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Fig 3 Expand

Fig 4.

Results for SpO2 (a), mTOI (b), mOxyHb (c), mDeOxyHb (d), mTotHb (e) at rest and at the end of the 3-min step-test (exercise). Values demonstrate the median, iqr, min, max values. Dots indicate the individual values of each participant. ⫪ p<0.001 main difference between environments, * p<0.001 to NN, # p = 0.008 to NH.

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Fig 4 Expand

Table 3.

Cardiovascular response to submaximal exercise.

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Table 3 Expand

Fig 5.

Results for PNSi (a), SNSi (b), LLAMS symptoms (c) using the LLAMS score, sleep quality ratings using the GSQS (d).

Values demonstrate the median, iqr, min, max values in 4a and 4b. Dots indicate the individual values of each participant. ⫪ p<0.05 main difference between environments, + p<0.05 to HH1, ‡ p<0.05 to HH2.

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Fig 5 Expand