Fig 1.
Survival in female CAD patients and healthy controls.
Kaplan Meier estimates including 95% point wise CIs are displayed in red for patients and blue for controls. The difference is quite obvious. The chance for surviving 26 years of follow up is below 50% for patients, compared to almost 60% of healthy controls. Considering the time points for 75% survival we find a time shift of 8.4 years (approx. 95% CI 4.2–12.6) in favor of controls.
Table 1.
Clinical, social and psychological characteristics of 286 female CAD patients at baseline and survival at 26 years follow-up.
Table 2.
Clinical, social and psychological characteristics of 299 healthy women at baseline and survival at 26 years follow-up.
Table 3.
Predictor models for women with CAD using Cox Boost analysis.
Fig 2.
Age and lack of social integration among older women with CAD.
There is an interaction between social integration and age. The predicted risk ratio for mortality increases with the degree of social isolation in older women (65 years) and decreases in younger women (45 years). This result could be plausible, as a lack of social integration could be an additional strain for older women.
Fig 3.
Predicting survival for exercise and non-smoking in women with CAD.
HRs do not allow quantifying effects on survival directly, therefore, predicted survival curves are displayed for a selection of covariates from the final model. For all plots, orange codes the baseline survival curve, cyan codes survival for relevant values of the covariate considered. a) Exercise. Moderate Exercise seems to be beneficial, showing an increase in survival of 20% appr. b) Smoking. Smokers might have a reduced chance of survival during follow up of up to 17% appr.
Fig 4.
Predicting survival for exercise in healthy women.
Moderate exercise seems to be beneficial, showing an increase in survival of 10% appr.
Table 4.
Model for controls after 26 years.