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Fig 1.

Schedule of enrollment, intervention and assessments.

IMP = Investigational Medicinal Product. CTG = Cardiotocography—continuous fetal heart tracing. VAS = Visual Analogue Scale. aPhysical Examination fetus includes fetal position and CTG—continuous fetal heart tracing bVital signs include maternal blood pressure and heart rate. Height and body weight are obtained from pregnancy charts cPhysical Examination newborn includes an examination of general appearance.

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Fig 2.

BUSCLAB trial design.

The flow chart summarizes the design of the BUSCLAB trial. *Crossing of the alert line for slow labor progress, according to the World Health Organization partograph. If the labor curve crosses to the right of the alert line, the cervical dilation rate is <1 cm per hour. NaCl = Sodium Chloride. IMP = Investigational Medicinal Product.

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Fig 2 Expand