Fig 1.
Workflow representing the overall design of the study.
The tasks listed in the green outlined boxes were applied only after the analyzed HPs showed the same function in at least three different bioinformatics tools.
Fig 2.
The gene ontology of all the 414 HPs.
(A) The distribution of the HPs among the three gene ontology categories. (B) Graph of the cellular components. (C) Graph of the biological processes. (D) Graph of the molecular functions. Here, the distribution of GO terms is presented on the Y axis and the area of the bubbles is relative to the number of proteins found in each category.
Fig 3.
A & B. Tertiary structures analysis. Three-dimensional structures were modeled by the SWISS-MODEL server reliably using the templates with higher coverage, more than 30% of identity, and higher GMQE scores along with Ramachandran Favored percentages ≥90%. Only the templates determined by the X-ray crystallography with high resolution were used. The known proteins and the modeled structures are indicated in red and blue colors respectively. The proteins are orientated using the Chimera MatchMaker according to the optimal superposition of the matching residues.
Table 1.
Hypothetical proteins functionally annotated from the B. paralicheniformis strain Bac84.
Table 2.
ROC results of the tools used in this study.