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Fig 1.

Mean radiotherapy dose map of the study population.

Overview of the mean radiotherapy dose distribution in the tumor-free hemisphere for the entire patient population, displayed on an T1 weighted MNI brain. Areas that received the highest RT dose (>20 Gy) included the parietal and occipital lobes and thalamus region. The temporal and frontal lobes received a lower dose (10–20 Gy) of RT.

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Table 1.

Demographic and clinical parameters.

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Fig 2.

Significant clusters for white matter volume loss per timepoint comparison.

Overview of the significant clusters for white matter volume loss of time-group comparisons. Different views of the tumor-free hemisphere are displayed. The local cluster color indicates the voxel t-value from the lowest value (red) to the highest (yellow) value. C and D indicate that volume loss is partially persistent over time. Abbreviations: RT = radiotherapy and TMZ = temozolomide.

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Fig 2 Expand

Table 2.

White matter volume differences per timepoint comparison.

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Table 2 Expand

Fig 3.

Significant clusters for gray matter volume loss per timepoint comparison.

Overview of the significant clusters for gray matter volume loss of time-group comparisons. Different views of the tumor-free hemisphere are displayed. The local color of the cluster indicates the voxel t-value from the lowest value (red) to the highest (yellow) value. Abbreviations: TMZ = temozolomide.

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Fig 3 Expand

Table 3.

Gray matter volume differences per timepoint comparison.

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Table 3 Expand