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Fig 1.

Flowchart of inclusion/exclusion criteria for the study population.

Abbreviations: RA rheumatoid arthritis; b/tsDMARD biologic or targeted synthetic disease-modifying anti-rheumatic drug; SCQM Swiss Clinical Quality Management in Rheumatic Diseases.

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Fig 1 Expand

Table 1.

Patient characteristics.

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Table 1 Expand

Fig 2.

Logistic regression assessing the effect of sex/gender on the study outcomes, with 12-month maximum follow-up.

Abbreviations: n number; OR odds ratio; ORadj odds ratio adjusted for age and seropositivity; DAS28 Disease Activity Score 28; rem/LDA remission or low disease activity; RADAI-5 Rheumatoid Arthritis Disease Activity Index-5.

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Fig 2 Expand

Table 2.

Sensitivity analysis.

Logistic regression assessing the effect of sex/gender on the study outcomes, with maximum follow-up of 9- and 15-months.

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Table 2 Expand

Table 3.

Summary findings from the mediation analyses (steps I and II), and findings from the main analysis for reference.

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Table 3 Expand