Table 1.
Demographic and clinical information between non-converters and converters.
Fig 1.
Survival curve for progression from MCI to dementia among participants with different CSF TNFα levels.
CSF TNFα was categorized into three groups according to tertiles of its levels. There was a significant difference in rates of conversion to dementia between three groups (tertiles of TNFα levels) among MCI individuals (p = 0.024).
Fig 2.
Summary of Cox proportional hazards regression model with CSF TNFα as the independent variable.
Compared to the low group (the reference group), the intermediate group progressed more rapidly to dementia [HR (95% CI) = 2.2 (1.15–4.1); p = 0.016] after adjusting for other covariates. However, the high group did not progress faster than the low group [HR (95% CI) = 1.5 (0.79–2.8); p = 0.214].