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Table 1.

DDIMDL dataset.

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Table 1 Expand

Fig 1.

Overall framework of the proposed model.

The changes in the node colors indicate the process of node learning, and H(l) and Z(l) indicate the vector representations learned at the lth layers of the DNN model and GCN model, respectively.

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Fig 1 Expand

Table 2.

Four different combinations of drug pairs.

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Table 2 Expand

Table 3.

Performance of our model against competitive approaches.

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Table 3 Expand

Table 4.

Ablation variants settings.

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Table 4 Expand

Fig 2.

Comparison of the ablation experiment results.

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Fig 2 Expand

Fig 3.

Statistical analysis of the DDI class distribution.

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Fig 3 Expand

Table 5.

Comparison of the link prediction results obtained over multiple classes.

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Table 5 Expand

Fig 4.

Distributions of the attention values over different classes.

(A) Attention distribution for Class_65. (B) Attention distribution for Class_30. (C) Attention distribution for Class_10.

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Fig 4 Expand

Fig 5.

Experimental results in different tasks.

(A) Task A. (B) Task B.

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Fig 5 Expand

Fig 6.

Results of ablation experiments.

(A) Effect of the number of GCN layers. (B) Effects of drug combination methods. (C) Effect of the fusion coefficient.

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Fig 6 Expand

Table 6.

Case study prediction results.

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Table 6 Expand

Fig 7.

Top 100 pairs of DDI prediction results.

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Fig 7 Expand