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Fig 1.

Recruitment flow chart.

UPCR = urine protein creatinine ratio.

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Fig 1 Expand

Table 1.

Patient baseline characteristics at native kidney biopsy.

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Table 1 Expand

Fig 2.

Frequencies of diagnoses.

UPCR = urine protein creatinine ratio; IgAN = Immunoglobulin A Nephritis; MCGN = minimal change glomerulonephritis; NP = nephropathy; TBMN = thin basement nephropathy; ATN = acute tubular necrosis; TMA = thrombotic microangiopathy; ANCA = anti-neutrophil cytoplasmic antibody.

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Fig 2 Expand

Fig 3.

a Kaplan-Meier survival analysis regarding composite endpoint (all-cause mortality, decrease of eGFR by >50% and ESKD) ESKD = end stage kidney disease. b Kaplan-Meier survival analysis regarding all-cause mortality end-stage kidney disease. c Kaplan-Meier survival analysis regarding >50% decrease from baseline eGFR. d Kaplan-Meier survival analysis regarding ESKD. e Cubic spline curve analysis reflecting adjusted hazard ratios and UPCR UPCR urine protein creatinine ratio.

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Fig 3 Expand

Table 2.

Patient outcomes by proteinuria-defined subgroup.

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Table 2 Expand

Table 3.

Risk of all-cause mortality and progression to end-stage kidney disease.

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Table 3 Expand

Table 4.

Subgroup analysis of subnephrotic range proteinuria.

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Table 4 Expand