Fig 1.
(a) High cellularity (×40). (b) Abundant microfollicles (×100). (c) Cell crowding and nuclear overlapping (×400). (d) Isolated cells (×100). (e) Abundant colloids (×40). (f) Homogeneous nuclei (×400).
Table 1.
Clinicodemographic patient characteristics (n = 98).
Table 2.
Cytologic features correlated with the final diagnoses of thyroid nodules.
Table 3.
US findings correlated with the final diagnoses of thyroid nodules.
Fig 2.
Images of a representative case of follicular adenoma.
A 59-year-old man was diagnosed with follicular adenoma on US. (a) An US image showing a 4.6 cm–sized oval predominantly solid isoechoic nodule with internal microcalcification. (b) US-guided FNA is performed with a 21-gauge syringe, and the nodule is suspicious for a follicular neoplasm. (c) The surgical specimen shows microfollicular proliferation with one macrofollicle containing three pieces of intrafollicular calcification corresponding to the ultrasonographic image shown in Fig 2A (arrows). ×40 original magnification. Hematoxylin and eosin staining is used. US, ultrasonography; FNA, fine-needle aspiration.
Fig 3.
Images of a representative case of follicular adenoma.
A 66-year-old woman was diagnosed with widely invasive follicular carcinoma. (a) An US image showing a 2.9 cm-sized heterogeneous ill-defined solid hypoechoic nodule with internal macrocalcification. (b) US-guided FNA is performed with a 21-gauge syringe, and the nodule appears to be a follicular lesion of undetermined significance. (c) The surgical specimen shows microfollicular proliferation with thick fibrous capsule with large pericapsular calcification corresponding to US image shown in Fig 3A (arrows). ×12.5 original magnification. Hematoxylin and eosin staining is used. US, ultrasonography; FNA, fine-needle aspiration.
Table 4.
Characteristics of the patients with follicular neoplasm with calcifications.