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Fig 1.

Search methodology and selection process.

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Table 1.

Main characteristics of studies included in the meta-analysis of the effects of L-carnitine on dialysis-related hypotension.

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Table 1 Expand

Table 2.

Risk of bias according to revised Cochrane risk-of-bias tool for randomized trials.

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Fig 2.

Forest plots of the included studies assessing odds ratio of dialysis-related hypotension.

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Fig 3.

a. Trial sequential analysis on the effect of L-carnitine on dialysis-related hypotension. b. Trial sequential analysis on the effect of L-carnitine on muscle cramps.

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Fig 3 Expand

Table 3.

Summary effects of L-carnitine and subgroup analysis on the route of L-carnitine supplementation, dose and duration of treatment on outcomes of interest among hemodialysis patients.

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Table 3 Expand

Table 4.

Comparison between previous meta-analysis and the present study.

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Table 4 Expand