Table 1.
Baseline table of the SPACE population.
Fig 1.
ROC curves to predict 30-day mortality (A) and ICU/MCU admission <3 days after ED presentation (B). The AUC of cv-ALL of monocytes to predict 30-day mortality (AUC = 0.61) was higher than the AUC of the clinical scores SIRS (AUC = 0.57) and qSOFA (AUC = 0.57), and comparable to MEWS (AUC = 0.61). For the prediction of ICU/MCU admission the AUC of cv-ALL of monocytes (AUC = 0.60) was slightly lower than the AUC of the clinical scores: SIRS (AUC = 0.61), qSOFA (AUC = 0.62), and MEWS (AUC = 0.66).
Fig 2.
ROC curves of the prediction of 30-day mortality (A) and ICU/MCU admission within 3 days after ED presentation (B). The optimal model consisted of the following parameters: cv-ALL of monocytes, age, sex, CCI, respiratory rate, systolic blood pressure, Glasgow Coma Scale, heart rate, leukocyte count, and body temperature. The AUC of the optimal model for prediction of 30-day mortality was 0.81 and for ICU/MCU admission <3 days 0.81 as well.
Table 2.
Univariate logistic regression for 30-day mortality.
Table 3.
AUC of clinical prediction scores with(out) cv-ALL of monocytes.