Table 1.
Comparison of apoptosis assays.
Fig 1.
An example of a flow cytometry plot showing stages of cell death.
Viable cells do not bind Annexin V or take up PI. Cells in early PCD bind Annexin V but still exclude PI. As the cell membrane becomes more permeable, cells in late PCD bind to Annexin V and PI. Dead or necrotic cells do not bind to Annexin V, but do take up PI.
Fig 2.
Induction of programmed cell death in an MCF-7 breast carcinoma and SNO oesophageal squamous cell carcinoma cell lines.
Fig 3.
Decreasing pH causes cell death in SNO cell line.