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Fig 1.

Connection overview.

All signals were subjected to electrical/optic conversion, optical transmission, and optic/electric conversion using Optic Input-Output modules (Optic I/O module A–C). The TTL signal was output from the PC at site A and recorded by the MEG data acquisition systems of each site. The timing standards were set using the TTL signal. The audio/video signal input/output unit serves as the communication device. The video signal is optically transmitted from the camera and presented from the projector via an A/V mixer. The audio signal is transmitted through the microphone, its latency matched to that of the video signal using an audio delay line, and then presented from the speaker via the A/V mixer. Photos: with permission by the models.

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Fig 2.

Video and audio signal latency distribution.

Video and audio signal latencies from site A to site B and those from site B to site A are superimposed. Audio signal latencies (red/blue bars on the left) are short and have no jitter, while video signal latencies (red/blue bars on the right) are longer and have some jitter (mean: 76.85 ms, SD: 6.57 ms) ranging from 60–100 ms. To optimize the setup for natural communication, audio signals can be delayed to match the latency of the video signals (white bar).

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Fig 3.

Amplitude modulation of alpha-band rhythm during face-to-face conversation.

redThe brain responses when two subjects faced each other via the A/V devices and spoke words in turns are shown. Mean alpha rhythm amplitude across 128 speech exchanges was normalized by the mean amplitude over the baseline period, from -2 and -1 s, to calculate Event Related Synchronization (ERS) and Event Related Desynchronization (ERD). The time traces of ERS/D averaged over the whole brain of each subject at site A (blue line) and B (green line) are shown on the upper panel. The brain activity of the subjects at both sites reflects that which is associated with listening, with time point 0 ms being the moment of speech onset of the opposite party. ERD of alpha rhythm is exhibited just before and during hearing the speech (mean: 0.7 s) of the opposite party. The brain surface images on the lower part show mean distributions of ERS (red; <+5%) and ERD (blue; >-5%) on each of the 15,002 vertices across both subjects; back-view (upper row) and left side-view (lower row). This mean alpha rhythm ERS/D was furthermore averaged temporally within each 0.5 s bin. A distinct ERD in the bilateral occipital region (visual area) and left temporal region (linguistic area) observed after 0 s indicate functional involvement of both the visual and auditory systems, suggesting that each subject could visually predict the onset of the opposite party’s speech. Abbreviations. L: Left, R: Right, A: Anterior, P: Posterior.

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