Fig 1.
Flow of participants throughout the study from recruitment to inclusion in final analysis.
Table 1.
Characteristics of the cohort prior to starting the first dietary intervention (n = 11).
Table 2.
Macronutrient energy intake, blood β-hydroxybutyrate (BOHB), and respiratory exchange ratio (RER) after the habitual diets of baseline and washout, and after the ketogenic diet (KD) and high-carbohydrate low-fat (HCLF) diet, for the whole cohort (n = 11).
Fig 2.
The individual changes in body mass (kg) during the dietary interventions.
Solid black lines: participants who did the ketogenic diet (KD) diet first (‘ba’ intervention sequence); Grey lines: participants who did the high-carbohydrate low-fat (HCLF) diet first (‘ab’ intervention sequence); dashed line: mean for all participants.
Table 3.
Outcome measures of change in body mass and thyroid function between the two dietary interventions (n = 11).
Fig 3.
The individual changes in circulating levels of thyroid stimulating hormone (TSH) (panel A), free thyroxine (T4; panel B) and triiodothyronine (T3; panel C) during the dietary interventions. Solid black lines: participants who did the ketogenic diet (KD) diet first (‘ba’ intervention sequence); Grey lines: participants who did the high-carbohydrate low-fat (HCLF) diet first (‘ab’ intervention sequence); dashed line: mean for all participants.