Fig 1.
Patients’ flow diagram by the 4 years studied at the 6 health facilities.
1) Eligible & analyzed for TPT uptake excluded the PLHIV eligible documented in the paper-based TPT register but had no information in the EMR. These were excluded because participants’ characteristics were extracted from the EMR. Numbers excluded were: 22, 30, 63, 380 in 2016, 2017, 2018 and 2019 respectively. 2) Numbers initiated on TPT among total patients eligible for TPT by year and quarter: 2016Q1 (875/31,306), 2016Q2 (90/3,127), 2016Q3 (24/2,378), 2016Q4 (407/1,871), 2017Q1 (343/32,333), 2017Q2 (294/3,308), 2017Q3 (442/2,325), 2017Q4 (266/1,634), 2018Q1 (78/30,867), 2018Q2 (78/5,394), 2018Q3 (131/2,251), 2018Q4 (296/1,815), 2019Q1 (4,802/25,694), 2019Q2 (2,448/11,061), 2019Q3 (1,269/2,073), 2019Q4 (516/1,658). 3) Majority of patients were scheduled to return to the HIV clinic for review every after 3 months. Number of patients visited during the quarter don’t add up to the unique numbers visited during the year.
Table 1.
Patients’ baseline characteristics at TPT uptake by year.
Fig 2.
a: Trend of TPT uptake across calendar years and quarters. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical black dashed line at 2019q3 indicates a point when the 100-day TPT accelerated campaign was rolled-out. b: Trend of predicted probabilities of TPT uptake by age groups. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical black dashed line at 2019q3 indicates a point when the 100-day TPT accelerated campaign was rolled-out. Points on line graph represent predicted probabilities of TPT uptake from GEE modified Poisson regression model with cluster standard errors to account for correlation of outcomes within each of the 6 clinics, adjusting for sex, age groups, ART status, WHO stage. Model was fitted with interaction between quarter of calendar year and age groups covariates. c: Trend of predicted probabilities of TPT uptake by sex. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical black dashed line at 2019q3 indicates a point when the 100-day TPT accelerated campaign was rolled-out. Points on line graph represent predicted probabilities of TPT uptake from modified Poisson GEE regression model with cluster standard errors to account for correlation of outcomes within each of the 6 clinics, adjusting for sex, age groups, ART status, WHO stage. Model was fitted with interaction between quarter of calendar year and sex covariates. d: Trend of predicted probabilities of TPT uptake by ART status. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical black dotted at 2019q3 line indicates a point when the 100-day TPT accelerated campaign was rolled-out. Points on line graph represent predicted probabilities of TPT uptake from modified Poisson GEE regression model with cluster standard errors to account for correlation of outcomes within each of the 6 clinics, adjusting for sex, age groups, ART status, WHO stage. Model was fitted with interaction between quarter of calendar year and sex covariates. e: Trend of predicted probabilities of TPT uptake by pregnancy status. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical black dotted at 2019q3 line indicates a point when the 100-day TPT accelerated campaign was rolled-out. Points on line graph represent predicted probabilities of TPT uptake from modified Poisson GEE regression model with cluster standard errors to account for correlation of outcomes within each of the 6 clinics, adjusting for sex, age groups, ART status, WHO stage. Model was fitted with interaction between quarter of calendar year and sex covariates.
Table 2.
Factors associated with TPT uptake.
Fig 3.
a: Trend of TPT completion by calendar years and quarters. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical dotted line at 2018q4 marks a point from which the 100-day TPT accelerated intervention targeted to achieve 100% completion. Trend graph truncated at 2019q2, a point which PLHIV initiated on TPT during the period studied were expected to have completed their 6-months TPT dose. b: Trend of predicted probabilities of TPT completion by age groups. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical dotted line at 2018q4 marks a point from which the 100-day TPT accelerated intervention targeted to achieve 100% completion. Trend graph truncated at 2019q2, a point which PLHIV initiated on TPT during the period studied were expected to have completed their 6-months TPT dose. c: Trend predicted probabilities of TPT uptake by sex. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical dotted line at 2018q4 marks a point from which the 100-day TPT accelerated intervention targeted to achieve 100% completion. Trend graph truncated at 2019q2, a point which PLHIV initiated on TPT during the period studied were expected to have completed their 6-months TPT dose. d: Trend of TPT completion by ART status. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical dotted line at 2018q4 marks a point from which the 100-day TPT accelerated intervention targeted to achieve 100% completion. Trend graph truncated at 2019q2, a point which PLHIV initiated on TPT during the period studied were expected to have completed their 6-months TPT dose. e: Trend predicted probabilities of TPT completion by pregnancy status. q1, q2, q3, and q4 denote quarters 1,2,3, and 4 respectively. The vertical dotted line at 2018q4 marks a point from which the 100-day TPT accelerated intervention targeted to achieve 100% completion. Trend graph truncated at 2019q2, a point which PLHIV initiated on TPT during the period studied were expected to have completed their 6-months TPT dose.
Table 3.
TPT completion and associated factors.