Fig 1.
Flowchart of patients with SARS-CoV-2 infection.
SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; and HFNC, high-flow nasal cannula.
Table 1.
Characteristics of patients with SARS-CoV-2 infection (N = 133).
Table 2.
Univariate and multivariable analyses of the predictive factors for HFNC failure.
Fig 2.
Receiver operator characteristic curves for ROX index and SpO2/FiO2 ratio as predictor of HFNC failure.
HFNC, high-flow nasal cannula; ROX, pulse oximetry/fraction of inspired oxygen/respiratory rate; AUROC, area under the receiver operating characteristic curve; CI = confidence interval; SpO2, percutaneous oxygen saturation; and FiO2, fraction of inspired oxygen. A. AUROC of ROX indices at 1 h and 4 h were 0.697 (95% CI: 0.597–0.798) and 0.682 (95% CI: 0.583–0.781), respectively. B. AUROC of SpO2/FiO2 ratios at 1 h and 4 h were 0.762 (95% CI: 0.679–0.846) and 0.733 (95% CI: 0.640–0.826), respectively.
Table 3.
Changes in respiratory variables of patients during HFNC (N = 133).
Table 4.
Univariate and multivariable analyses of the predictive factors for in-hospital mortality.