Table 1.
Baseline demographics and clinical characteristics of the COVID-19 study cohort.
Fig 1.
Increased severity of COVID-19 is associated with higher levels of endothelial cell activation and fibrinolysis biomarkers.
The plasma levels of A) VWF, B) sP-Selectin, and C) D-dimer were measured in blood samples obtained from COVID-19 patients. Lines denote median levels with error bars representing minimum and maximum values. Sample sizes: No O2 (N = 20), O2 Rx (N = 20), HFNC (N = 15), Vent (N = 19), and Dead (N = 9). *p < 0.05 compared to No O2 group; ^p < 0.05 compared to O2 group; +p < 0.05 compared to HFNC group.
Table 2.
Spearman correlations* between biomarkers of endothelial cell activation, fibrinolysis, inflammation, and vascular injury.