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Fig 1.

Flowchart of patient inclusion and data selection.

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Table 1.

Patient characteristics and median duration of recorded vital signs during three-day observation period.

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Fig 2.

Mean of vital signs during three day observation period in each cohort.

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Table 2.

Coefficients of cosinor models.

Recovered patients are compared to patients with respiratory insufficiency and deceased patients.

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Table 2 Expand

Fig 3.

Progression of cosinor characteristics over the course of three days for heart rate, respiratory rate and skin temperature, stratified by cohort.

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Fig 3 Expand

Table 3.

Differences in cosinor mixed effect model amplitudes (difference, 99%CI) between days for the A. recovery cohort, B. respiratory insufficiency cohort, and C. mortality cohort.

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Table 3 Expand