Fig 1.
MAEBASHI COVID-19 PROTOCOL (included the lung-protective strategy): Lung-protective ventilation with neuromuscular blocking agents, early application of prone positioning, and prolonged prone positioning. Abbreviations: P/F = PaO2/FIO2; PBW = predicted body weight; Vt = Tidal Volume (mL); Pplat = plateau airway pressure; NMBA = neuromuscular blocking agent; V-V ECMO = veno-venous extracorporeal membrane oxygenation; SAT = spontaneous awakening test; SBT = spontaneous breathing test.
Fig 2.
We identified 96 patients over 18-years-old with coronavirus disease 2019 (COVID-19) pneumonia in our intensive care unit (ICU); 26 patients did not receive invasive ventilation, and 2 patients who underwent veno-venous extracorporeal membrane oxygenation in a referring hospital were excluded. A total of 68 patients were included in the analysis, with 18 in the pre-introduction group and 50 in the post-introduction group.
Table 1.
Baseline characteristics.
Table 2.
Parameters of ventilation and prone positioning and complications related to prone positioning.
Table 3.
Primary and secondary outcomes.